Description

3-Cyclopropyl-1-(4-Methoxyphenyl)-6-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. Its complex molecular architecture makes it a critical building block for the research and development of novel therapeutic agents, particularly in oncology and antiviral applications. This compound is essential for medicinal chemists and pharmaceutical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final chemical structure of investigational new drugs (INDs).
• Biochemical Research: Employed as a tool compound to study specific biological pathways and enzyme interactions.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material production.

Basic Information

Product Name	3-Cyclopropyl-1-(4-Methoxyphenyl)-6-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011399-73-7
Molecular Formula	C20H17N3O3
Molecular Weight	347.37 g/mol
Synonyms	3-Cyclopropyl-1-(4-methoxyphenyl)-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 3-cyclopropyl-1-(4-methoxyphenyl)-6-methyl-; 1011399-73-7; 3-Cyclopropyl-1-(p-methoxyphenyl)-6-methylpyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Methyl-3-cyclopropyl-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-1-(4-Methoxyphenyl)-6-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	≤ 2.0% total
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.