Description

6-[4-(Difluoromethoxy)Phenyl]-3-Methyl-1-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in the research and development of novel active pharmaceutical ingredients (APIs), particularly for its role as a key synthetic building block. It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting specific enzyme inhibition.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures for specialized applications.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of investigational new drugs.

Basic Information

Product Name	6-[4-(Difluoromethoxy)Phenyl]-3-Methyl-1-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011398-87-0
Molecular Formula	C23H17F2N3O3
Molecular Weight	421.40 g/mol
Synonyms	6-[4-(Difluoromethoxy)phenyl]-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-[4-(difluoromethoxy)phenyl]-3-methyl-1-phenyl-; DFMP-Pyrazolopyridine Carboxylic Acid; CAS 1011398-87-0; 6-(4-(Difluoromethoxy)phenyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-[4-(Difluoromethoxy)Phenyl]-3-Methyl-1-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.