Description

3-Cyclopropyl-6-[4-(Difluoromethoxy)Phenyl]-1-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, particularly in the development of targeted therapies. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Critical intermediate in the research and development of new pharmaceutical compounds.
• Building block for the synthesis of potential kinase inhibitors and other targeted small-molecule drugs.
• Used in preclinical and process chemistry studies for route scouting and optimization.
• Key starting material (KSM) or advanced intermediate in the manufacture of active pharmaceutical ingredients (APIs).
• Valuable reference standard for analytical method development and quality control in pharmaceutical production.
• Employed in academic and industrial research exploring the structure-activity relationships (SAR) of pyrazolopyridine derivatives.

Basic Information

Item	Detail
Product Name	3-Cyclopropyl-6-[4-(Difluoromethoxy)Phenyl]-1-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011398-84-7
Molecular Formula	C20H17F2N3O3
Molecular Weight	385.36 g/mol
Synonyms	1-Methyl-3-cyclopropyl-6-[4-(difluoromethoxy)phenyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-[4-(Difluoromethoxy)phenyl]-1-methyl-3-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 3-Cyclopropyl-6-(4-(difluoromethoxy)phenyl)-1-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; CAS 1011398-84-7; Pyrazolo[3,4-b]pyridine-4-carboxylic acid derivative; DFMP-Pyrazolopyridine intermediate
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-6-[4-(Difluoromethoxy)Phenyl]-1-Methyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing all specifications are provided and available upon request to ensure full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The material may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.