Description

(3-Methyl-5-Nitro-Pyrazolo[3,4-B]Pyridin-1-Yl)-Acetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and other targeted therapy areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted small-molecule therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its pyrazolopyridine scaffold.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for preclinical and clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	(3-Methyl-5-Nitro-Pyrazolo[3,4-B]Pyridin-1-Yl)-Acetic Acid
CAS No.	1011398-78-9
Molecular Formula	C11H10N4O4
Molecular Weight	262.22 g/mol
Synonyms	1-(Carboxymethyl)-3-methyl-5-nitropyrazolo[3,4-b]pyridine; 2-[(3-Methyl-5-nitro-1H-pyrazolo[3,4-b]pyridin-1-yl)]acetic Acid; (3-Methyl-5-nitro-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic Acid; 1011398-78-9; Pyrazolo[3,4-b]pyridine-1-acetic acid, 3-methyl-5-nitro-; 1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 3-methyl-5-nitro-
EINECS	Contact for details

Quality Control

Our (3-Methyl-5-Nitro-Pyrazolo[3,4-B]Pyridin-1-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.