Description

6-Cyclopropyl-1-(2-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound matters as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation drug candidates with potential applications in oncology and central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Chemical Biology Research: Used as a core scaffold for designing and screening compound libraries in drug discovery programs.
• API Development: Serves as a critical building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of heterocyclic compounds.

Basic Information

Product Name	6-Cyclopropyl-1-(2-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011398-69-8
Molecular Formula	C₁₇H₁₂FN₃O₂
Molecular Weight	309.30 g/mol
Synonyms	6-Cyclopropyl-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1-(2-Fluorophenyl)-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Cyclopropyl-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic Acid; 1011398-69-8; 6-Cyclopropyl-1-(2-fluorophenyl)pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Cyclopropyl-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (ACI); SCHEMBL2180156
EINECS	Contact for details

Quality Control

Our 6-Cyclopropyl-1-(2-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.