Description

5-Chloro-1-(2-Fluorophenyl)-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-value, multi-functional heterocyclic building block with significant potential in advanced organic synthesis. Its complex pyrazolopyridine core, functionalized with chloro, fluoro, and carboxylic acid groups, makes it a versatile intermediate for constructing sophisticated molecular architectures. This compound is primarily targeted at research and development laboratories in the pharmaceutical and agrochemical sectors, where it serves as a critical precursor for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapy programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	5-Chloro-1-(2-Fluorophenyl)-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011398-61-0
Molecular Formula	C₁₇H₁₃ClFN₃O₂
Molecular Weight	345.76 g/mol
Synonyms	5-Chloro-1-(2-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 5-chloro-1-(2-fluorophenyl)-3,6-dimethyl-; 1011398-61-0; 5-Chloro-1-(2-fluorophenyl)-3,6-dimethylpyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Pyrazolo[3,4-b]pyridinecarboxylic acid, 5-chloro-1-(2-fluorophenyl)-3,6-dimethyl-
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(2-Fluorophenyl)-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our commitment to quality supports your R&D and regulatory needs with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.