Description

1-(2-Fluorophenyl)-6-Thien-2-Yl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic assays and target validation studies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) optimization in drug discovery projects.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up production.
• Academic Research: Utilized in university and institutional labs for investigating new chemical entities and their biological activities.

Basic Information

Product Name	1-(2-Fluorophenyl)-6-Thien-2-Yl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011398-29-0
Molecular Formula	C₁₇H₁₀FN₃O₂S
Molecular Weight	339.34 g/mol
Synonyms	1-(2-Fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-(Thiophen-2-yl)-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1011398-29-0; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(2-fluorophenyl)-6-(2-thienyl)-; Fluorophenyl-thienyl-pyrazolopyridine-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluorophenyl)-6-Thien-2-Yl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.