Description

1-[2-(Cyclopropylamino)-2-Oxoethyl]-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1011398-12-1. This compound is a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), valued for its defined heterocyclic structure which enables targeted molecular modifications. It is primarily required by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing next-generation therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing final API molecules in regulated GMP production.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific enzyme interactions and pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-[2-(Cyclopropylamino)-2-Oxoethyl]-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011398-12-1
Molecular Formula	C16H18N4O3
Molecular Weight	314.34 g/mol
Synonyms	3,6-Dimethyl-1-[2-(cyclopropylamino)-2-oxoethyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-[2-(cyclopropylamino)-2-oxoethyl]-3,6-dimethyl-; CPAPC; Cyclopropylamino Pyrazolopyridine Carboxylic Acid; 1011398-12-1; UNII-7K1JNU5R0I; 7K1JNU5R0I
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects with traceable documentation and can align with GMP guidelines for advanced production stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.