Description

6-[4-(Difluoromethoxy)Phenyl]-1-(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of new-generation pesticides and herbicides, leveraging its complex heterocyclic structure.
• Biochemical Tool Compound: Employed in biochemical assays and as a probe to study enzyme function and cellular signaling pathways.
• Custom Synthesis Building Block: Provides a sophisticated core structure for contract research organizations (CROs) and fine chemical suppliers performing bespoke synthesis.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-[4-(Difluoromethoxy)Phenyl]-1-(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011397-92-4
Molecular Formula	C22H14F3N3O3
Molecular Weight	425.36 g/mol
Synonyms	6-[4-(Difluoromethoxy)phenyl]-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1-(4-Fluorophenyl)-6-[4-(difluoromethoxy)phenyl]pyrazolo[3,4-b]pyridine-4-carboxylic acid; Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-; CAS 1011397-92-4; 1011397-92-4
EINECS	Contact for details

Quality Control

Our 6-[4-(Difluoromethoxy)Phenyl]-1-(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.