Description

1-(4-Fluorophenyl)-6-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1011397-67-3. This compound is a critical building block in modern medicinal chemistry, valued for its role in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and anti-inflammatory drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Kinase Inhibitor Synthesis: Used in the construction of complex heterocyclic cores for potential kinase-targeting therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in academic and industrial R&D labs.
• API Development: Integral to the process chemistry for manufacturing investigational new drugs (INDs).
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific biological pathways and target interactions.

Basic Information

Product Name	1-(4-Fluorophenyl)-6-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011397-67-3
Molecular Formula	C19H12FN3O2
Molecular Weight	333.32 g/mol
Synonyms	1-(4-Fluorophenyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 4-Pyrazolo[3,4-b]pyridinecarboxylic acid, 1-(4-fluorophenyl)-6-phenyl-1H-; 1011397-67-3; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(4-fluorophenyl)-6-phenyl-; 6-Phenyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-6-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.