Description

3-Cyclopropyl-1-(4-Fluorophenyl)-6-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities targeting various disease pathways.
• Kinase Inhibitor Development: Its pyrazolopyridine core is a privileged structure in the design of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the creation of tool compounds for probing biological function and validating novel drug targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Cyclopropyl-1-(4-Fluorophenyl)-6-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011397-43-5
Molecular Formula	C22H16FN3O2
Molecular Weight	373.38 g/mol
Synonyms	3-Cyclopropyl-1-(4-fluorophenyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 3-cyclopropyl-1-(4-fluorophenyl)-6-phenyl-; 1011397-43-5; 3-Cyclopropyl-1-(p-fluorophenyl)-6-phenylpyrazolo[3,4-b]pyridine-4-carboxylic Acid; 6-Phenyl-3-cyclopropyl-1-(4-fluorophenyl)pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-1-(4-Fluorophenyl)-6-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.