Description

6-Cyclopropyl-1-[2-(Isopropylamino)-2-Oxoethyl]-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development. The product, CAS NO 1011396-85-2, is supplied under stringent quality control to ensure batch-to-batch consistency for critical R&D and scale-up applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially within kinase inhibitor research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex pyrazolopyridine-based molecular architectures.
• Research & Development (R&D): Essential for academic and industrial labs exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of target APIs.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for client-specific synthesis projects.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	6-Cyclopropyl-1-[2-(Isopropylamino)-2-Oxoethyl]-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011396-85-2
Molecular Formula	C18H22N4O3
Molecular Weight	342.40 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-cyclopropyl-1-[2-[(1-methylethyl)amino]-2-oxoethyl]-3-methyl-; 6-Cyclopropyl-3-methyl-1-(2-oxo-2-(propylamino)ethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; UNII-4B6I9Q6F4F; 4B6I9Q6F4F; 6-Cyclopropyl-1-[2-(isopropylamino)-2-oxoethyl]-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Cyclopropyl-3-methyl-1-[2-oxo-2-(propan-2-ylamino)ethyl]pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Cyclopropyl-1-[2-(Isopropylamino)-2-Oxoethyl]-3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.