Description

3-Cyclopropyl-1,6-Bis(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is valued for its complex heterocyclic core, which serves as a critical building block in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of novel chemical entities.
• Academic Research: Employed in university and institutional labs for investigating new heterocyclic chemistry and biological activity.

Basic Information

Product Name	3-Cyclopropyl-1,6-Bis(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011396-68-1
Molecular Formula	C28H19F2N3O2
Molecular Weight	467.47 g/mol
Synonyms	3-Cyclopropyl-1,6-bis(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1,6-Bis(4-fluorophenyl)-3-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 3-Cyclopropyl-1,6-di-p-fluorophenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 3-cyclopropyl-1,6-bis(4-fluorophenyl)-; CAS 1011396-68-1
EINECS	Contact for details

Quality Control

Our production of 3-Cyclopropyl-1,6-Bis(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade and GMP-starting material standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.