Description

1-Methyl-6-Pyridin-3-Yl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid CAS NO 1011396-62-5 is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its complex fused pyrazolopyridine-pyridine structure makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology Probe Development: Serves as a core scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential building block for organic electronic materials, such as ligands in coordination polymers or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up activities.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	1-Methyl-6-Pyridin-3-Yl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1011396-62-5
Molecular Formula	C14H10N4O2
Molecular Weight	266.26 g/mol
Synonyms	1-Methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1-Methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1011396-62-5; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-methyl-6-(3-pyridinyl)-; 6-(Pyridin-3-yl)-1-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Methyl-6-Pyridin-3-Yl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.