Description

n-(5-Amino-2-Pyridinyl)-4-Trifluoromethylbenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine and benzamide structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its trifluoromethyl group for enhanced bioactivity and stability.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or ligands for catalytic systems.
• Contract Research & Development (CRO/CMO): Supplied to organizations conducting custom synthesis and process development for clients.

Basic Information

Product Name	n-(5-Amino-2-Pyridinyl)-4-Trifluoromethylbenzamide
CAS No.	1011244-68-0
Molecular Formula	C13H10F3N3O
Molecular Weight	281.24 g/mol
Synonyms	4-(Trifluoromethyl)-N-(5-amino-2-pyridinyl)benzamide; 5-Amino-N-[4-(trifluoromethyl)phenyl]pyridine-2-carboxamide; 2-Pyridinecarboxamide, 5-amino-N-[4-(trifluoromethyl)phenyl]-; N-(5-Amino-2-pyridyl)-4-(trifluoromethyl)benzamide; 1011244-68-0; 4-Trifluoromethyl-N-(5-amino-2-pyridinyl)benzamide
EINECS	Contact for details

Quality Control

Our n-(5-Amino-2-Pyridinyl)-4-Trifluoromethylbenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.