Description

(2,6-Dichloropyridin-3-Yl)(8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for enabling sophisticated synthetic routes in modern drug discovery, particularly for targeting central nervous system (CNS) disorders. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including kinase inhibitors and neuroactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for the development and optimization of potent and selective kinase inhibitors.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic benefits.
• Preclinical Drug Development: Employed in the synthesis of compounds for pharmacological profiling, toxicology studies, and early-stage development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	(2,6-Dichloropyridin-3-Yl)(8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone
CAS No.	1010905-74-4
Molecular Formula	C17H12Cl2FN3O
Molecular Weight	364.20 g/mol
Synonyms	8-Fluoro-2-[(2,6-dichloropyridin-3-yl)carbonyl]-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole; 1010905-74-4; (2,6-Dichloro-3-pyridinyl)(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)methanone; Methanone, (2,6-dichloro-3-pyridinyl)(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-; 8-Fluoro-2-(2,6-dichloropyridine-3-carbonyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
EINECS	Contact for details

Quality Control

Our (2,6-Dichloropyridin-3-Yl)(8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.