Description

(4,6-Dimethoxy-1-Methyl-1H-Indol-2-Yl)[4-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Piperidin-1-Yl]Methanone is a sophisticated heterocyclic compound that serves as a critical pharmaceutical intermediate and research chemical. Its unique molecular architecture, combining indole and triazolopyridine moieties, makes it a valuable building block for medicinal chemistry research and drug discovery programs. This compound is primarily utilized by R&D teams in the pharmaceutical and biotechnology sectors for the synthesis and development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in vitro and in vivo to study biological pathways and validate novel drug targets, particularly those involving specific receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and research institutions engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	(4,6-Dimethoxy-1-Methyl-1H-Indol-2-Yl)[4-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Piperidin-1-Yl]Methanone
CAS No.	1010903-04-4
Molecular Formula	C23H25N5O3
Molecular Weight	419.48 g/mol
Synonyms	4,6-Dimethoxy-1-methyl-2-{[4-([1,2,4]triazolo[4,3-a]pyridin-3-yl)piperidin-1-yl]carbonyl}-1H-indole; 1H-Indole-2-methanone, 4,6-dimethoxy-1-methyl-, 4-(1,2,4-triazolo[4,3-a]pyridin-3-yl)-1-piperidinyl deriv.; [4-(1,2,4-Triazolo[4,3-a]pyridin-3-yl)piperidin-1-yl](4,6-dimethoxy-1-methyl-1H-indol-2-yl)methanone; CAS 1010903-04-4
EINECS	Contact for details

Quality Control

Our (4,6-Dimethoxy-1-Methyl-1H-Indol-2-Yl)[4-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Piperidin-1-Yl]Methanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.