Description

(2-Chloropyridin-3-Yl)(8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone is a sophisticated heterocyclic building block and key intermediate in modern pharmaceutical research. This compound matters for its role as a crucial scaffold in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and oncology drug discovery pipelines. Pharmaceutical R&D teams and fine chemical manufacturers need this high-purity intermediate to synthesize and evaluate new chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for CNS disorders and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new pharmacophores.
• Biochemical Tool Compound: Acts as a reference standard or probe in biological assays to investigate specific enzyme or receptor interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.
• Pre-clinical Development: Employed in the synthesis of compounds for pharmacokinetic, pharmacodynamic, and toxicology studies.

Basic Information

Item	Details
Product Name	(2-Chloropyridin-3-Yl)(8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone
CAS No.	1010895-57-4
Molecular Formula	C18H13ClFN3O
Molecular Weight	341.77 g/mol
Synonyms	8-Fluoro-2-[(2-chloropyridin-3-yl)carbonyl]-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole; (2-Chloro-3-pyridinyl)(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)methanone; 1010895-57-4; 8-Fluoro-2-(2-chloropyridine-3-carbonyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole; Methanone, (2-chloro-3-pyridinyl)(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-
EINECS	Contact for details

Quality Control

Our (2-Chloropyridin-3-Yl)(8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indol-2-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request, and we support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.