Description

5-Bromo-3-Methyl-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, ligand synthesis, and the development of functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the pyridine core and halogenated groups contribute to biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science: Incorporated into the design of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology: Utilized as a probe or tag in bioconjugation chemistry and for modifying biomolecules.
• Custom Synthesis & Scale-Up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	5-Bromo-3-Methyl-2-(Trifluoromethyl)Pyridine
CAS No.	1010422-52-2
Molecular Formula	C8H5BrF3N
Molecular Weight	252.03 g/mol
Synonyms	2-(Trifluoromethyl)-5-bromo-3-methylpyridine; 3-Methyl-5-bromo-2-(trifluoromethyl)pyridine; 5-Bromo-3-methyl-2-trifluoromethylpyridine; Pyridine, 5-bromo-3-methyl-2-(trifluoromethyl)-; 1010422-52-2
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Methyl-2-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.