Description

Pyridine, 2,6-Dichloro-3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional heterocyclic building block featuring a pyridine core substituted with a pinacol boronate ester group. This compound is specifically engineered for advanced synthetic chemistry, serving as a critical intermediate in the construction of complex molecules via cross-coupling reactions. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the boronate ester for efficient carbon-carbon bond formation.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents due to its reactive boronate handle.
• Catalyst & Ligand Development: Utilized to synthesize novel chelating ligands for transition metal catalysts used in fine chemical production.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific projects.

Basic Information

Product Name	Pyridine, 2,6-Dichloro-3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1010101-08-2
Molecular Formula	C14H18BCl2NO2
Molecular Weight	314.01 g/mol
Synonyms	2,6-Dichloro-3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-dichloro-3-methylpyridine; 2,6-Dichloro-3-methylpyridine-4-boronic acid pinacol ester; 3-Methyl-2,6-dichloro-4-pyridineboronic acid pinacol ester; (2,6-Dichloro-3-methylpyridin-4-yl)boronic acid pinacol ester; Pinacol (2,6-dichloro-3-methylpyridin-4-yl)boronate
EINECS	Contact for details

Quality Control

Our Pyridine, 2,6-Dichloro-3-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.