Description

5-Chloro-6-(2-Methylpropoxy)Pyridine-3-Carboxylic Acid is a high-purity pyridine derivative and a key synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized structure, which serves as a versatile building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, particularly in the synthesis of potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up activities.

Basic Information

Product Name	5-Chloro-6-(2-Methylpropoxy)Pyridine-3-Carboxylic Acid
CAS No.	1008769-66-1
Molecular Formula	C10H12ClNO3
Molecular Weight	229.66 g/mol
Synonyms	5-Chloro-6-isobutoxynicotinic Acid; 3-Pyridinecarboxylic acid, 5-chloro-6-(2-methylpropoxy)-; 5-Chloro-6-(2-methylpropoxy)nicotinic Acid; 5-Chloro-6-isobutoxy-3-pyridinecarboxylic Acid; 1008769-66-1; 5-Chloro-6-(isobutoxy)nicotinic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-6-(2-Methylpropoxy)Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.