Description

3-Bromo-6-Iodo-2-Methylpyridine is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which provides distinct reactive sites for selective cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyridine core for biological activity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, enabling the construction of complex biaryl and heterobiaryl systems.
• Ligand Synthesis: Utilized for preparing novel nitrogen-containing ligands for catalysis in asymmetric synthesis and transition metal complexes.
• Chemical Biology: Acts as a versatile probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies and bio-conjugation.

Basic Information

Product Name	3-Bromo-6-Iodo-2-Methylpyridine
CAS No.	1008361-77-0
Molecular Formula	C6H5BrIN
Molecular Weight	297.92 g/mol
Synonyms	2-Methyl-3-bromo-6-iodopyridine; 6-Iodo-3-bromo-2-methylpyridine; 3-Bromo-6-iodo-2-picoline; Pyridine, 3-bromo-6-iodo-2-methyl-; 2-Picoline, 3-bromo-6-iodo-
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Iodo-2-Methylpyridine is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.