Description

1-[(1-Ethyl-3-Methyl-1H-Pyrazol-4-Yl)Sulfonyl]Proline is a specialized proline derivative featuring a sulfonyl-linked pyrazole moiety, designed for advanced synthetic applications. This compound is valued for its role as a key chiral building block and intermediate in the development of complex bioactive molecules. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for drug discovery, process chemistry, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and synthesis of new drug candidates, particularly in protease inhibitor and peptidomimetic development.
• Agrochemical Research: Used as a building block in the discovery and production of novel pesticides and herbicides with enhanced activity.
• Peptide Chemistry: Serves as a modified amino acid residue for constructing structurally diverse peptides with improved metabolic stability or binding affinity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-up: An intermediate for optimizing synthetic routes during the scale-up from laboratory to pilot plant or commercial production.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Product Name	1-[(1-Ethyl-3-Methyl-1H-Pyrazol-4-Yl)Sulfonyl]Proline
CAS No.	1008008-25-0
Molecular Formula	C11H17N3O4S
Molecular Weight	287.34 g/mol
Synonyms	L-Proline, 1-[(1-ethyl-3-methyl-1H-pyrazol-4-yl)sulfonyl]-; (S)-1-((1-Ethyl-3-methyl-1H-pyrazol-4-yl)sulfonyl)pyrrolidine-2-carboxylic acid; 1-[(1-Ethyl-3-methylpyrazol-4-yl)sulfonyl]proline; Proline sulfonyl pyrazole derivative; 1-(1-Ethyl-3-methyl-1H-pyrazol-4-ylsulfonyl)proline; 1008008-25-0; 1-(1-Ethyl-3-methyl-1H-pyrazol-4-ylsulfonyl)-L-proline
EINECS	Contact for details

Quality Control

Our 1-[(1-Ethyl-3-Methyl-1H-Pyrazol-4-Yl)Sulfonyl]Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.