Description

Methyl 6-Bromo-2-Fluoro-3-Methoxybenzoate is a high-purity fluorinated and brominated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated structure makes it an essential building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for its role in facilitating challenging synthetic transformations.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated benzoate core.
• Ligand and Material Science Precursor: Serves as a starting material for synthesizing specialized ligands for catalysis or advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the scalable production of client-specific target molecules.
• Academic and Industrial R&D: A valuable reagent for methodological studies in cross-coupling reactions, fluorination chemistry, and heterocycle formation.

Basic Information

Product Name	Methyl 6-Bromo-2-Fluoro-3-Methoxybenzoate
CAS No.	1007455-28-8
Molecular Formula	C9H8BrFO3
Molecular Weight	263.06 g/mol
Synonyms	Methyl 6-bromo-2-fluoro-3-methoxybenzoate; 6-Bromo-2-fluoro-3-methoxybenzoic acid methyl ester; Benzoic acid, 6-bromo-2-fluoro-3-methoxy-, methyl ester; 2-Fluoro-6-bromo-3-methoxybenzoic acid methyl ester; Methyl 2-fluoro-6-bromo-3-methoxybenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Bromo-2-Fluoro-3-Methoxybenzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support customer-specific analytical method verification upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.