Description

[3-Cyclopropyl-4-(Difluoromethyl)-6-(1-Ethyl-5-Methyl-1H-Pyrazol-4-Yl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeting specific biological pathways. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Development: Serves as a core structural component in the development and scale-up of new Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed as a tool compound or probe in biochemical and pharmacological assays to study enzyme inhibition or receptor binding.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and process development projects.

Basic Information

Product Name	[3-Cyclopropyl-4-(Difluoromethyl)-6-(1-Ethyl-5-Methyl-1H-Pyrazol-4-Yl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	1006478-14-3
Molecular Formula	C19H19F2N5O2
Molecular Weight	387.38 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 3-cyclopropyl-4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-; 3-Cyclopropyl-4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-ylacetic acid; (3-Cyclopropyl-4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; CAS 1006478-14-3
EINECS	Contact for details

Quality Control

Our [3-Cyclopropyl-4-(Difluoromethyl)-6-(1-Ethyl-5-Methyl-1H-Pyrazol-4-Yl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.