Description

[6-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid CAS NO 1006477-44-6 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating pyrazole and pyridopyrazole moieties. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis.
• API Development: Integral in the process development and scale-up of new Active Pharmaceutical Ingredients (APIs) targeting specific biological pathways.
• Biochemical Tool Compound: May be utilized in vitro as a probe or inhibitor to study enzyme function and cellular mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Agrochemical Research: Potential application in the development of new agrochemicals due to its heterocyclic framework.

Basic Information

Product Name	[6-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	1006477-44-6
Molecular Formula	C16H14F3N5O2
Molecular Weight	365.31 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 6-(1,5-dimethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-; (6-(1,5-Dimethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; Acetic acid, [6-(1,5-dimethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]-; 1006477-44-6; 6-(1,5-Dimethyl-1H-pyrazol-4-yl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-ylacetic Acid
EINECS	Contact for details

Quality Control

Our production of [6-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-3-Methyl-4-(Trifluoromethyl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.