Description

(1-Methyl-1H-Pyrazol-4-Yl)-Pyridin-3-Ylmethyl-Amine CAS NO 1006446-26-9 is a high-purity heterocyclic amine building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. Its unique bifunctional structure makes it an essential reagent for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic amine core for bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and exploring new chemical spaces.

Basic Information

Product Name	(1-Methyl-1H-Pyrazol-4-Yl)-Pyridin-3-Ylmethyl-Amine
CAS No.	1006446-26-9
Molecular Formula	C10H12N4
Molecular Weight	188.23 g/mol
Synonyms	3-[(1-Methyl-1H-pyrazol-4-yl)amino]methylpyridine; 1-Methyl-4-[(pyridin-3-ylmethyl)amino]-1H-pyrazole; N-[(1-Methyl-1H-pyrazol-4-yl)methyl]pyridin-3-amine; (1-Methyl-1H-pyrazol-4-yl)methyl-pyridin-3-yl-amine; 3-(((1-Methyl-1H-pyrazol-4-yl)amino)methyl)pyridine; Pyridine, 3-[[(1-methyl-1H-pyrazol-4-yl)amino]methyl]-; 1006446-26-9
EINECS	Contact for details

Quality Control

Our (1-Methyl-1H-Pyrazol-4-Yl)-Pyridin-3-Ylmethyl-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material that meets stringent internal specifications, suitable for use under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.