Description

[4-(Difluoromethyl)-6-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and other specialized fields.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Development: Serves as a core scaffold for constructing complex molecules in oncology and other high-value therapeutic pipelines.
• Chemical Biology Probes: Utilized in the development of specialized probes for target identification and validation in biological systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	[4-(Difluoromethyl)-6-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	1006444-98-9
Molecular Formula	C16H15F2N5O2
Molecular Weight	347.32 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 4-(difluoromethyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-; 4-(Difluoromethyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-ylacetic acid; (4-(Difluoromethyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; CAS 1006444-98-9
EINECS	Contact for details

Quality Control

Our [4-(Difluoromethyl)-6-(1,3-Dimethyl-1H-Pyrazol-4-Yl)-3-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and returned to storage immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.