Description

[4-(Difluoromethyl)-3-Methyl-6-(1-Methyl-1H-Pyrazol-4-Yl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid CAS NO 1006444-93-4 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and agrochemical industries for developing next-generation small molecule drugs and crop protection agents.

Application

This specialized intermediate serves critical functions in advanced chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the research and development of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its unique pyrazolopyridine core.
• Chemical Research & Development: Serves as a valuable scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex active molecules.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	[4-(Difluoromethyl)-3-Methyl-6-(1-Methyl-1H-Pyrazol-4-Yl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	1006444-93-4
Molecular Formula	C15H13F2N5O2
Molecular Weight	333.30 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 4-(difluoromethyl)-3-methyl-6-(1-methyl-1H-pyrazol-4-yl)-; 4-(Difluoromethyl)-3-methyl-6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-ylacetic acid; [4-(Difluoromethyl)-3-methyl-6-(1-methylpyrazol-4-yl)pyrazolo[3,4-b]pyridin-1-yl]acetic acid; DFMMPPA (abbreviation); Pyrazolopyridine acetic acid derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of [4-(Difluoromethyl)-3-Methyl-6-(1-Methyl-1H-Pyrazol-4-Yl)-1H-Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.