Description

1-(5-Nitropyridin-2-Yl)-1H-Pyrazole-3-Carboxylic Acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its nitro and carboxylic acid functionalities.
• Chemical Biology Probe Synthesis: Employed in creating molecular tools and probes for studying biological processes and target identification.
• Material Science Research: Serves as a building block for novel organic electronic materials or metal-organic frameworks (MOFs) due to its conjugated system and coordinating sites.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(5-Nitropyridin-2-Yl)-1H-Pyrazole-3-Carboxylic Acid
CAS No.	1006443-01-1
Molecular Formula	C9H6N4O4
Molecular Weight	234.17 g/mol
Synonyms	1-(5-Nitropyridin-2-yl)-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 1-(5-nitro-2-pyridinyl)-; 1-(5-Nitro-2-pyridyl)-1H-pyrazole-3-carboxylic acid; 2-(3-Carboxy-1H-pyrazol-1-yl)-5-nitropyridine; 5-Nitro-2-(3-carboxy-1H-pyrazol-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(5-Nitropyridin-2-Yl)-1H-Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.