Description

(1R,2R)-Ethyl2-(3,4-Difluorophenyl)Cyclopropane Carboxylate is a high-purity, chiral cyclopropane derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the chiral cyclopropane structure confers specific biological activity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new asymmetric catalytic processes.
• Fine Chemical Building Block: Utilized in custom synthesis and the production of complex, high-value specialty chemicals.
• Material Science Research: Investigated for the synthesis of novel organic materials and liquid crystals due to its rigid, fluorinated structure.

Basic Information

Product Name	(1R,2R)-Ethyl2-(3,4-Difluorophenyl)Cyclopropane Carboxylate
CAS No.	1006376-61-9
Molecular Formula	C12H12F2O2
Molecular Weight	226.22 g/mol
Synonyms	(1R,2R)-Ethyl 2-(3,4-Difluorophenyl)cyclopropanecarboxylate; Ethyl (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylate; (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxylic Acid Ethyl Ester; trans-Ethyl 2-(3,4-difluorophenyl)cyclopropanecarboxylate; (1R,2R)-Rel-2-(3,4-Difluorophenyl)cyclopropanecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our (1R,2R)-Ethyl2-(3,4-Difluorophenyl)Cyclopropane Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard identification tests, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.