Description

6-(Trifluoromethyl)H-Imidazo[1,2-A]Pyridin-2-Amine is a high-value, nitrogen-containing heterocyclic compound featuring a trifluoromethyl group, which imparts unique physicochemical properties critical for advanced synthesis. This specialized building block is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for creating compounds with enhanced metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products, leveraging the trifluoromethyl group to improve lipophilicity and biological activity.
• Chemical Biology Probe Development: Serves as a core scaffold for designing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a precursor for organic electronic materials and metal-organic frameworks (MOFs) due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	6-(Trifluoromethyl)H-Imidazo[1,2-A]Pyridin-2-Amine
CAS No.	1005785-87-4
Molecular Formula	C8H6F3N3
Molecular Weight	201.15 g/mol
Synonyms	6-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-amine; 2-Amino-6-(trifluoromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridin-2-amine, 6-(trifluoromethyl)-; 1005785-87-4; 6-Trifluoromethylimidazo[1,2-a]pyridin-2-ylamine; 6-(Trifluoromethyl)-2-imidazo[1,2-a]pyridinamine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed using advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.