Description

Piperidine-1,4,4-Tricarboxylic Acid 1-tert-Butyl Ester 4-Methyl Ester is a high-purity, multi-functional piperidine derivative used as a critical building block in advanced organic synthesis. Its value lies in providing a protected carboxylic acid framework, enabling precise and efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require a functionalized piperidine core.
• Peptidomimetics & Bioactive Molecule Design: Serves as a constrained scaffold for mimicking peptide structures and creating libraries of bioactive compounds.
• Ligand & Catalyst Development: Employed in the synthesis of complex chelating ligands and organocatalysts for asymmetric synthesis.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals for clients.
• Academic & Industrial Research: Facilitates methodological studies in organic chemistry, including novel ring-forming reactions and protection/deprotection strategies.

Basic Information

Product Name	Piperidine-1,4,4-Tricarboxylic Acid 1-tert-Butyl Ester 4-Methyl Ester
CAS No.	1005738-45-3
Molecular Formula	C14H23NO6
Molecular Weight	301.34 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-(methoxycarbonyl)piperidine-4-carboxylic Acid; 1-Boc-4-(COOMe)piperidine-4-COOH; 4-Carboxy-1-N-Boc-piperidine-4-carboxylic Acid Methyl Ester; 1-N-Boc-4-methoxycarbonylisonipecotic Acid; 4-(Methoxycarbonyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic Acid; tert-Butyl 4-(methoxycarbonyl)-4-carboxypiperidine-1-carboxylate; Piperidine-1,4,4-tricarboxylic Acid 1-tert-Butyl 4-Methyl Diester
EINECS	Contact for details

Quality Control

Every batch of our Piperidine-1,4,4-Tricarboxylic Acid 1-tert-Butyl Ester 4-Methyl Ester is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and cGMP manufacturing applications. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.