Description

3-Amino-4-(1-Ethyl-3-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with improved efficacy and safety profiles.
• API Development: Integral in the research and process development stages for creating new Active Pharmaceutical Ingredients, leveraging its thienopyridine and pyrazole motifs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the pharmaceutical industry.
• Biochemical Reagent: May be utilized as a specialized reagent or reference standard in biochemical assays and screening libraries.

Basic Information

Product Name	3-Amino-4-(1-Ethyl-3-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide
CAS No.	1005696-22-9
Molecular Formula	C15H14F3N5OS
Molecular Weight	369.37 g/mol
Synonyms	3-Amino-4-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)-; CAS 1005696-22-9
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(1-Ethyl-3-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.