Description

3-Amino-4-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation drug candidates, leveraging its unique chemical properties to create molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new drug molecules, especially in oncology and central nervous system (CNS) therapeutic areas.
• Kinase Inhibitor Synthesis: Used in the construction of complex heterocyclic cores found in potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clinical trials.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic synthesis and pharmaceutical sciences.

Basic Information

Item	Detail
Product Name	3-Amino-4-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide
CAS No.	1005632-64-3
Molecular Formula	C15H12F3N5OS
Molecular Weight	367.35 g/mol
Synonyms	3-Amino-4-(1,5-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,5-dimethyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)-; 1005632-64-3; 3-Amino-4-(1,5-dimethylpyrazol-4-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(1,5-Dimethyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.