Description

3-(4-Bromo-Pyrazol-1-Yl)-2-Methyl-Propionic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its pyrazole core and ester functionality. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted small molecule drugs, including kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides due to its bioactive pyrazole scaffold.
• Medicinal Chemistry: Serves as a versatile precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	3-(4-Bromo-Pyrazol-1-Yl)-2-Methyl-Propionic Acid Methyl Ester
CAS No.	1005615-47-3
Molecular Formula	C8H11BrN2O2
Molecular Weight	247.09 g/mol
Synonyms	Methyl 3-(4-bromo-1H-pyrazol-1-yl)-2-methylpropanoate; Methyl 2-methyl-3-(4-bromo-1H-pyrazol-1-yl)propanoate; 3-(4-Bromo-1H-pyrazol-1-yl)-2-methylpropionic acid methyl ester; 1H-Pyrazole-1-propanoic acid, 4-bromo-, 2-methyl-, methyl ester; 4-Bromo-1-(2-methoxycarbonyl-1-methylethyl)pyrazole
EINECS	Contact for details

Quality Control

Our production of 3-(4-Bromo-Pyrazol-1-Yl)-2-Methyl-Propionic Acid Methyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.