Description

3-Amino-6-(difluoromethyl)-4-(1-ethyl-5-methyl-1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Oncology Drug Development: Serves as a core scaffold for the development of potential kinase inhibitors and other targeted cancer therapies.
• Antiviral Agent Synthesis: Employed in the research and development of new antiviral compounds.
• Chemical Biology Probes: Used to create specialized molecular probes for studying enzyme function and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	3-Amino-6-(difluoromethyl)-4-(1-ethyl-5-methyl-1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
CAS No.	1005582-49-9
Molecular Formula	C16H15F2N5OS
Molecular Weight	363.39 g/mol
Synonyms	Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-6-(difluoromethyl)-4-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-; 3-Amino-6-(difluoromethyl)-4-(1-ethyl-5-methyl-1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxylic acid amide; CAS 1005582-49-9
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-6-(difluoromethyl)-4-(1-ethyl-5-methyl-1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications suitable for pharmaceutical research applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Single Maximum Impurity	≤1.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.