Description

3-Amino-4-(1-Ethyl-5-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide is a high-value, complex heterocyclic compound featuring a fused thienopyridine core with a pyrazole substituent and a trifluoromethyl group. This sophisticated molecular architecture makes it a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing new drugs, particularly in areas like kinase inhibitors and targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Oncology Drug Development: The structural motifs present are common in compounds being investigated for anti-cancer properties.
• Chemical Biology Probes: Utilized in the development of specialized molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for client-specific synthetic routes and scale-up projects.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals due to its heterocyclic structure.

Basic Information

Product Name	3-Amino-4-(1-Ethyl-5-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide
CAS No.	1005566-12-0
Molecular Formula	C15H14F3N5OS
Molecular Weight	369.37 g/mol
Synonyms	3-Amino-4-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)-; 1005566-12-0; 3-Amino-4-(1-ethyl-5-methylpyrazol-4-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; 4-(1-Ethyl-5-methyl-1H-pyrazol-4-yl)-6-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide-3-amine
EINECS	Contact for details

Quality Control

Our production of 3-Amino-4-(1-Ethyl-5-Methyl-1H-Pyrazol-4-Yl)-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2-Carboxamide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Our quality system is designed to meet the exacting standards of the global pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under inert atmosphere to maximize stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.