Description

(E)-3-(2-Propyl-6-(Trifluoromethyl)Pyridin-3-Yl)Acrylic Acid is a high-value fluorinated pyridine derivative and an important pharmaceutical intermediate. This compound is prized for its unique molecular scaffold, which combines a trifluoromethyl group with an acrylic acid moiety, enabling its use in the synthesis of advanced active ingredients. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated molecules for improved potency and pharmacokinetics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialty polymers and advanced materials with specific surface properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs) in chemical research.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research focused on the synthesis and reactivity of fluorinated heterocycles.

Basic Information

Product Name	(E)-3-(2-Propyl-6-(Trifluoromethyl)Pyridin-3-Yl)Acrylic Acid
CAS No.	1005174-17-3
Molecular Formula	C12H12F3NO2
Molecular Weight	259.22 g/mol
Synonyms	(E)-3-[2-Propyl-6-(trifluoromethyl)-3-pyridinyl]-2-propenoic acid; 3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acid; trans-3-(2-Propyl-6-(trifluoromethyl)-3-pyridinyl)acrylic acid; 2-Propenoic acid, 3-[2-propyl-6-(trifluoromethyl)-3-pyridinyl]-, (2E)-; (E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)propenoic acid; 1005174-17-3; (E)-3-(2-Propyl-6-(trifluoromethyl)-3-pyridinyl)acrylic acid
EINECS	Contact for details

Quality Control

Our production of (E)-3-(2-Propyl-6-(Trifluoromethyl)Pyridin-3-Yl)Acrylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.