Description

6-Chloro-4-(Trifluoromethyl)Nicotinaldehyde is a high-value, multi-functional chemical building block characterized by its reactive aldehyde group and halogenated pyridine core. This compound is essential for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used to construct advanced active ingredients for herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its unique electronic properties imparted by the halogen and trifluoromethyl substituents.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	6-Chloro-4-(Trifluoromethyl)Nicotinaldehyde
CAS No.	1005171-96-9
Molecular Formula	C7H3ClF3NO
Molecular Weight	209.55 g/mol
Synonyms	6-Chloro-4-(trifluoromethyl)pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 6-chloro-4-(trifluoromethyl)-; 6-Chloro-4-trifluoromethylnicotinaldehyde; 6-Chloro-4-(trifluoromethyl)-3-pyridinecarboxaldehyde; 6-Chloro-4-(trifluoromethyl)nicotinaldehyde; 6-Chloro-4-(trifluoromethyl)-3-formylpyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-4-(Trifluoromethyl)Nicotinaldehyde is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our products are developed to meet the stringent requirements of research and pre-clinical development phases. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, GC, NMR, and MS is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.