Description

1,6-Naphthyridine-2-Carboxylic Acid Ethyl Ester is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its rigid, bicyclic heteroaromatic structure, which serves as a key scaffold in medicinal chemistry and advanced material synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules targeting various disease pathways.
• Agrochemical Research: Used as a core structure for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials, such as semiconductors and light-emitting components.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: A key building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	1,6-Naphthyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	1005030-66-9
Molecular Formula	C11H10N2O2
Molecular Weight	202.21 g/mol
Synonyms	Ethyl 1,6-Naphthyridine-2-carboxylate; 2-Ethoxycarbonyl-1,6-naphthyridine; 1,6-Naphthyridine-2-carboxylic Acid Ethyl Ester; Ethyl 1,6-Naphthyridin-2-carboxylate; 1,6-Naphthyridin-2-carboxylic acid, ethyl ester; 2-Carbethoxy-1,6-naphthyridine; 1,6-Naphthyridine-2-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom purity grades, including research and GMP standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.