Description

3-Bromoimidazo[1,2-A]Pyridine-6-Carbaldehyde is a high-value brominated heterocyclic building block, specifically a functionalized imidazopyridine derivative. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile precursor for the synthesis of novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of bioactive molecules targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its reactive aldehyde and bromo functional groups.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Material Science: Potential precursor for organic electronic materials or metal-organic frameworks (MOFs) requiring specific heterocyclic ligands.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis: Employed in parallel and combinatorial chemistry for the rapid generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	3-Bromoimidazo[1,2-A]Pyridine-6-Carbaldehyde
CAS No.	1004550-20-2
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	3-Bromoimidazo[1,2-a]pyridine-6-carboxaldehyde; 6-Formyl-3-bromoimidazo[1,2-a]pyridine; 3-Bromo-6-formylimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-carboxaldehyde, 3-bromo-; 1004550-20-2
EINECS	Contact for details

Quality Control

Our 3-Bromoimidazo[1,2-A]Pyridine-6-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.