Description

1-(5-Bromopyridin-3-Yl)Cyclopropanamine Hcl is a high-purity, advanced pharmaceutical intermediate featuring a unique bromopyridine-cyclopropylamine scaffold. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and metabolic disorders. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in neuroscience and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile bromine and amine functional groups.
• Chemical Library Synthesis: Serves as a valuable scaffold for creating diverse compound libraries for high-throughput screening.
• Kinase Inhibitor Development: Employed in the research and development of small molecule kinase inhibitors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-(5-Bromopyridin-3-Yl)Cyclopropanamine Hydrochloride
CAS No.	1003856-13-0
Molecular Formula	C8H10BrN2•HCl
Molecular Weight	263.54 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)cyclopropanamine hydrochloride; 1-(5-Bromopyridin-3-yl)cyclopropan-1-amine hydrochloride; 3-(1-Aminocyclopropyl)-5-bromopyridine hydrochloride; 5-Bromo-3-(1-aminocyclopropyl)pyridine HCl; Cyclopropanamine, 1-(5-bromo-3-pyridinyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Yl)Cyclopropanamine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.