Description

4-Iodo-2-Nitropyridine is a versatile halogenated nitropyridine derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring both iodine and nitro functional groups, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry for creating targeted libraries.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other conjugated systems.
• Nucleophilic Aromatic Substitution: The nitro group activates the pyridine ring for substitution reactions, enabling further functionalization.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	4-Iodo-2-Nitropyridine
CAS No.	1003711-88-3
Molecular Formula	C5H3IN2O2
Molecular Weight	249.99 g/mol
Synonyms	2-Nitro-4-iodopyridine; 4-Iodo-2-nitropyridine; Pyridine, 4-iodo-2-nitro-; 4-Iodopyridine, 2-nitro-
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-Nitropyridine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.