Description

4-Chloro-3-Ethoxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and ethoxy substituents, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for creating tagged molecules or inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	4-Chloro-3-Ethoxypyridine
CAS No.	1003711-81-6
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	3-Ethoxy-4-chloropyridine; 4-Chloro-3-ethoxypyridine; 4-Chloro-3-ethoxy-pyridine; Pyridine, 4-chloro-3-ethoxy-; 1003711-81-6
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Ethoxypyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.