Description

5-Fluoro-2-Hydroxy-3-Nitro-4-Picoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring fluorine, nitro, and hydroxy substituents on a pyridine core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and nitro group can enhance biological activity and environmental stability.
• Ligand Synthesis: Acts as a starting material for creating sophisticated chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Advanced Material Development: Utilized in the research of novel organic electronic materials and metal-organic frameworks (MOFs) due to its functionalized aromatic system.

Basic Information

Product Name	5-Fluoro-2-Hydroxy-3-Nitro-4-Picoline
CAS No.	1003711-68-9
Molecular Formula	C6H5FN2O3
Molecular Weight	172.11 g/mol
Synonyms	5-Fluoro-3-nitro-2-pyridinol; 5-Fluoro-2-hydroxy-3-nitropyridine; 3-Nitro-5-fluoro-2(1H)-pyridinone; 5-Fluoro-3-nitro-2(1H)-pyridone; 2-Hydroxy-3-nitro-5-fluoropyridine; 5-Fluoro-3-nitro-2-pyridone; 4-Picoline, 5-fluoro-2-hydroxy-3-nitro-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Hydroxy-3-Nitro-4-Picoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.