Description

5-Chloro-2-Fluoro-3-Hydroxypyridine is a high-purity halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine and chlorine substituents for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers used in specialty polymers and coordination chemistry.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and fine chemical manufacturers engaged in bespoke synthesis projects.

Basic Information

Product Name	5-Chloro-2-Fluoro-3-Hydroxypyridine
CAS No.	1003711-65-6
Molecular Formula	C5H3ClFNO
Molecular Weight	147.53 g/mol
Synonyms	3-Hydroxy-5-chloro-2-fluoropyridine; 2-Fluoro-5-chloro-3-hydroxypyridine; 5-Chloro-2-fluoro-3-pyridinol; 3-Pyridinol, 5-chloro-2-fluoro-; 1003711-65-6
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-3-Hydroxypyridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity by HPLC, identification by IR and NMR, and impurity profiles are available for every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.