Description

2-Bromo-5-Cyano-6-Picoline is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functional groups for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized pyridine-based ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-5-Cyano-6-Picoline
CAS No.	1003711-39-4
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	6-Bromo-3-cyano-2-picoline; 2-Bromo-5-cyano-6-methylpyridine; 6-Methyl-3-cyano-2-bromopyridine; 2-Bromo-6-methyl-5-cyanopyridine; 5-Cyano-2-bromo-6-methylpyridine; 2-Bromo-5-cyano-6-picoline; 2-Bromo-6-picoline-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Cyano-6-Picoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.