Description

2-Bromo-5-Cyano-4-Picoline is a versatile halogenated pyridine derivative that serves as a crucial building block in advanced organic synthesis. Its unique structure, featuring both bromine and cyano substituents, makes it a highly valuable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its reactive halogen and nitrile functional groups.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Bromo-5-Cyano-4-Picoline
CAS No.	1003711-35-0
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	4-Picoline, 2-bromo-5-cyano-; 2-Bromo-5-cyano-4-methylpyridine; 4-Methyl-2-bromo-5-cyanopyridine; 5-Cyano-2-bromo-4-picoline; 2-Bromo-5-cyano-4-methylpyridine; 2-Bromo-4-methyl-5-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Cyano-4-Picoline is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure high purity and consistency for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.