Description

2-Amino-5-Fluoro-3-Hydroxypyridine is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its molecular structure, featuring amino, fluoro, and hydroxyl substituents on a pyridine core, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in fine chemical and material science applications.
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds due to its electron-donating and accepting capabilities.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, molecular probes, and other tools in diagnostic and life science research.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and academic laboratories engaged in novel heterocyclic chemistry.

Basic Information

Product Name	2-Amino-5-Fluoro-3-Hydroxypyridine
CAS No.	1003711-04-3
Molecular Formula	C5H5FN2O
Molecular Weight	128.10 g/mol
Synonyms	5-Fluoro-3-hydroxy-2-pyridinamine; 3-Hydroxy-5-fluoro-2-pyridinamine; 2-Amino-5-fluoro-3-pyridinol; 5-Fluoro-2-amino-3-hydroxypyridine; 2-Pyridinamine, 5-fluoro-3-hydroxy-; 1003711-04-3; 2-Amino-5-fluoro-3-pyridinone (tautomeric form)
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoro-3-Hydroxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical and advanced chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.